Affiliation
Date
Publisher
Journal Title
Journal ISSN
Volume Title
Abstract
Mutation of the Chx10 homeobox gene in mice and humans causes congenital blindness and microphthalmia (small eyes). This study used Chx10-/- (ocular retardation) mice to investigate how lack of Chx10 affects progenitor/stem cell behavior in the retina and ciliary epithelium (CE).The distribution of mitotic retinal progenitor cells (RPCs) during embryonic...
Description
Keywords
DNA Replication , 570 , 610 , Embryonic Development , Apoptosis , Nerve Tissue Proteins , Retina , Mice , In Situ Nick-End Labeling , Animals , Fluorescent Antibody Technique, Indirect , Pigment Epithelium of Eye , Cell Proliferation , Homeodomain Proteins , Neurons , Stem Cells , Cell Cycle , Ciliary Body , Flow Cytometry , Mice, Mutant Strains , Biomarkers , Transcription Factors