Abstract
ObjectiveEarly diagnosis of natalizumab-related progressive multifocal leucoencephalopathy (NTZ-PML) in multiple sclerosis has been deemed a major priority by the regulatory agencies but has yet to become a reality. The current paper aims to: (1) investigate whether patients with NTZ-PML pass through a prolonged presymptomatic phase with MRI abnormalities, (2) estimate...
Description
Keywords
Adult , Male , Multiple Sclerosis , Surgery; Neurology (clinical); Psychiatry and Mental Health , Natalizumab , Leukoencephalopathy, Progressive Multifocal , 610 , natalizumab; progressive multifocal leucoencephalopathy; natalizumab treatment , Middle Aged , Magnetic Resonance Imaging , Adult; Early Diagnosis; Female; Humans; Immunologic Factors; Italy; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Natalizumab; Retrospective Studies; Young Adult , Settore MED/26 - NEUROLOGIA , Young Adult , Early Diagnosis , Italy , Surgery; Neurology (clinical); Psychiatry and Mental Health, progressive multifocal leucoencephalopathy , Humans , Immunologic Factors , Female , Retrospective Studies